The research in my laboratory is directed at understanding how chromosome structure affects gene regulation, and how gene expression affects genome stability.

Many diseases – chief among them cancer – exhibit genome instability, chromosome rearrangement, transposable element mobilizations, and hypermutation.  The source of these instabilities is not generally know, but growing evidence links it to the ribosomal DNA and nucleolus, the subjects of study in my laboratory.

We use the fruit fly Drosophila melanogaster, whose unparalleled tools in genetics, genome manipulation, and epigenetics allows us to develop, test, and refine hypotheses relevant to human disease.


Epigenetic Instability


Ribosomal DNA

Nuclear Function

welcome to

the Maggert Laboratory


Regular Goings-On

Updated 2017-02-22

Regular Meetings

Ted Weinert's Journal Club — Fridays 3:30p LSS 4th floor conference room

Genome Rearrangements

Julie successfully defendes her M.S. dissertation! Congratulations Master Jules!!

In the news..!

AZPM public radio interview