The research in my laboratory is directed at understanding how chromosome structure affects gene regulation, and how gene expression affects genome stability.

Many diseases – chief among them cancer – exhibit genome instability, chromosome rearrangement, transposable element mobilizations, and hypermutation.  The source of these instabilities is not generally know, but growing evidence links it to the ribosomal DNA and nucleolus, the subjects of study in my laboratory.

We use the fruit fly Drosophila melanogaster, whose unparalleled tools in genetics, genome manipulation, and epigenetics allows us to develop, test, and refine hypotheses relevant to human disease.


Epigenetic Instability

Heterochromatin Function

Ribosomal DNA

Nuclear Function

welcome to

the Maggert Laboratory


Keith A. Maggert is a recipient of the 2016 National Institutes of Health Transformative Research Award, a part of the High-Risk-High-Reward program!




Updated 2016-10-02

Regular Meetings

GEICO/ICER — Fridays 9a UACC 2nd floor conference room

Ted Weinert's Journal Club — Fridays 12:30n LSS 4th floor conference room